Pharmacy Technician Certification Board Practice Exam

What is a common side effect of long-term opioid use?

1. Headaches

2. Respiratory depression

3. Weight gain

4. Hair loss

The correct answer is: Respiratory depression

Long-term opioid use can lead to respiratory depression, which is a condition characterized by slower and shallower breathing. Opioids act on the central nervous system to provide pain relief, but their primary mechanism also involves depressing the respiratory drive. This is particularly concerning because it can lead to inadequate oxygenation of the body and potentially life-threatening situations, especially if the dosage is not properly managed or if the patient has additional respiratory issues. While headaches, weight gain, and hair loss may be side effects associated with various medications or underlying conditions, they are not typically linked to opioids in the same way that respiratory depression is. Thus, understanding the risks associated with opioid therapy is crucial for both healthcare providers and patients to ensure safe and effective pain management.