Pharmacy Technician Certification Board Practice Exam

What is the maximum quantity of isotretinoin (Accutane) that can be dispensed at one time?

1. 15-day supply

2. 30-day supply

3. 60-day supply

4. 90-day supply

The correct answer is: 30-day supply

Isotretinoin, sold under the brand name Accutane, is a powerful medication used to treat severe acne. Due to its side effects and potential risks, including pregnancy-related birth defects, there are strict regulations surrounding its distribution. The maximum quantity that can be dispensed at one time is a 30-day supply. This regulation is in place to ensure close monitoring of the patient's therapy and to mitigate the risks associated with the drug. By limiting the dispensing to a 30-day supply, healthcare providers can evaluate the patient's progress, manage any adverse effects, and reinforce the necessary precautions about potential side effects, particularly for female patients regarding pregnancy. This dispensing limit is consistent with guidelines from the FDA and the iPLEDGE program, which oversees the safe distribution of isotretinoin. In contrast, a 15-day supply would not allow enough time for proper assessment of treatment efficacy and side effects, while a 60-day or 90-day supply would increase the risk of patients experiencing side effects without adequate monitoring and counseling.