Pharmacy Technician Certification Board Practice Exam

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Which of the following is an example of a progesterone-only contraceptive (POC)?

  1. Ethinyl estradiol/drospirenone (Yaz)

  2. Ethinyl estradiol/etonogestrel (NuvaRing)

  3. Levonorgestrel (Mirena)

  4. Ethinyl estradiol/norgestimate (Estarylla)

The correct answer is: Levonorgestrel (Mirena)

Levonorgestrel, sold under the brand name Mirena, is a prime example of a progesterone-only contraceptive (POC). POCs contain progestin only, which effectively prevents ovulation and creates a hostile environment for sperm, reducing the chances of fertilization. Mirena is a specific intrauterine device (IUD) that releases levonorgestrel directly into the uterus. This localized delivery minimizes systemic hormones in circulation while providing highly effective long-term contraception, typically lasting up to five years. In contrast, the other options combine estrogen with progestin. Ethinyl estradiol/drospirenone (Yaz), ethynil estradiol/etonogestrel (NuvaRing), and ethinyl estradiol/norgestimate (Estarylla) are all combination hormonal contraceptives. These formulations contain both estrogen and progestin, which is a different mechanism of action compared to progesterone-only contraceptives. Understanding the distinctions between these contraceptive options is crucial for determining the appropriate choice for patients based on their individual health needs and preferences.