Pharmacy Technician Certification Board Practice Exam

Which side effect is commonly associated with oral prednisolone use?

1. Hypoglycemia

2. Weight loss

3. Increased risk of infection

4. Fluid loss

The correct answer is: Increased risk of infection

Oral prednisolone, a corticosteroid, is often used to suppress inflammation and modify the immune response in various conditions. One of the notable side effects associated with its use is an increased risk of infection. This occurs because corticosteroids can modulate the immune system by reducing the number of circulating white blood cells and impairing the function of immune cells. As a result, patients on prednisolone may be more susceptible to infections, including bacterial, viral, and fungal, as their body's ability to respond effectively is diminished. Other potential side effects include weight gain, fluid retention, and hyperglycemia; however, the specific side effect of increased risk of infection stands out as a critical concern that healthcare providers must monitor in patients taking this medication. Thus, recognizing the increased risk of infection as a side effect is essential for appropriate patient care and management.